Remdesivir Antivirus Trial Shows Positive Results

Good news comes from the United States amid the corona virus pandemic which is in most countries around the world.

Treatment of corona virus patients conducted at a hospital in Chicago using remdesivir, an antiviral drug produced by the US biotechnology company, Gilead Sciences Inc. is showing positive results.

At present the hospital is conducting clinical trials on the drug.

The clinical trial was closely monitored to see rapid recovery in fever and respiratory symptoms, with almost all patients discharged in less than a week.

Launching STAT News, remdesivir was one of the first drugs identified as having the potential to impact SARS-CoV-2, a new type of corona virus that causes Covid-19 in laboratory tests.

Gilead clinical trial results are eagerly awaited.

And positive results will likely lead to quick approval by the Food and Drug Administration and other regulatory and drug regulatory bodies.

If it is safe and effective, it can be an approved treatment for the first time against Covid-19 disease.

The University of Chicago Department of Medicine recruited 125 people with Covid-19 into two Gilead Phase 3 clinical trials.

Of these people, 113 had severe illness. All patients were treated with remdesivir infusion every day.
“The best news is that most of our patients are out, this is good. We only lost (died) two patients, “said Kathleen Mullane, an infectious disease specialist at the University of Chicago who oversees remdesivir research for hospitals.

His comments were delivered this week during a video discussion about the results of the trial with other University of Chicago faculty members.

• Corona Virus Test No Need to RS with Drive Thru Service, Available in Indonesia

The discussion was recorded and STAT News obtained a copy of the video.

The results only show a portrait of the effectiveness of remdesivir.

However, no other clinical data from the Gilead study have been released to date.

Last month, President of the United States, Donald Trump touted the potential of remdesivir as he has for many treatments that have not yet been proven, and said that “it seems (treatment with remdesivir) has very good results.”

In a statement on Thursday, Gilead said: “What we can say at this stage is that we are waiting for data from ongoing studies (to) be available.”

Gilead said they expect results for tests involving severe cases in April.

Mullane said during his presentation that data for the first 400 patients in the study would be “locked” by Gilead on Thursday, meaning that the results could come at any time.

Favipiravir Antiviral Drug Tested in Corona Patients

A number of doctors have now begun testing the drug favipiravir to treat corona virus patients, arguing that the anti-virus efficacy of this drug can be utilized. The flu drug, with the trade name Avigan, was granted a permit in Japan in 2014. Preliminary results indicate that this cold medicine could shorten the recovery time for Covid-19 patients.

China’s ministry of science and technology said the drug showed “very good clinical results”. There are currently five clinical trials in several countries, including in Italy, Japan and the United States. Fujifilm Toyama Chemical said the drug efficacy trials were carried out in groups of 100 patients until the end of June.

Studies in Japan will give the drug for more than 14 days to patients in the age range of 20 to 74 years. “His research will monitor a variety of factors,” Gaetan Burgio, a geneticist at the Australian National University’s College of Health and Medicine, told the AFP news agency.

These include, clinically important effects on fever, coughing, oxygenation, recovery period and hospital stay. Also observed how quickly the virus is cleaned from the system along with x-ray or CT scan for pneumonia.

“If we see a significant reduction in clinical trial results and a lower viral load in the group of patients given favipiravir, this would be a good indication for clinical trials on a larger scale,” said geneticist Burgio.

Strict standard trial

Favipiravir trials to treat corona virus are carried out to a very strict standard. The aim is to ensure that the drug is safe and effective in a large number of patients.

“Smaller studies already have reports. But it is difficult to draw conclusions, because the number of patients is very small, and there is no comparison given a placebo. More often than other drugs,” said Stephen Griffin, a virologist from the University of Leeds, England.

Favipiravir works by blocking the virus to multiply in cells. So far there are still concerns regarding its safety. Because in laboratory tests, this flu drug affects the development of the fetus in the womb. Therefore doctors are advised not to give drugs to pregnant women.

Orders flooded, factories speeding production

The Favipiravir flu drug, with the trade name Avigan, is only permitted in Japan to treat flu outbreaks that cannot be treated with existing medicines. This drug also does not exist in the public market. Favirapir may only be produced and distributed at the request of the Japanese government.

Now the government in Tokyo ordered Fujifilm to boost its production. Both for domestic needs and to meet the demands of more than a dozen countries that have submitted applications for the import of drugs.

It is said, a number of countries in Asia, including Indonesia, have ordered this cold medicine in large doses. Also Germany and the United States have submitted applications to purchase Avigan to the Japanese government.

Acquire The Help You Are Going To Require To Be Able To Change Your Locks

When a person acquires a brand new property, they are going to have to have keys made for each person in their own family. Before they go on and accomplish this, nonetheless, they could wish to contemplate having the locks changed. They could have a look at the locksmiths near me to be able to discover one who might help them change out all of the locks inside the property.

The reason individuals want to change the locks without delay is to make sure no person might enter the house whenever they are not there. Although they could have been advised they were provided all replicates of the keys, this is not always accurate. The individual might have been presented all the keys the real estate professional knew about, but there might be ones the previous house owner didn’t remember. Anytime this takes place, there might be somebody that will make use of the keys to be able to enter the property after the brand new homeowner moves in. In order to stop this, and to be able to ensure there aren’t any keys the house owner doesn’t know about, changing the locks will be required.

In the event you happen to be searching for a locksmith to help you change the locks inside your brand new home, speak to one who has been servicing milwaukee for 20 years. They’ll have the ability in order to assist you to have all of the locks changed as fast as possible. Contact them now in order to understand more.

The Old Temple of Athena Polias

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Farther along the Sacred Way we notice the foundations of an ancient temple in front of the Erechtheion. On account of its length of 100 Attic feet, this edifice was wrongly believed for centuries to be the Hecatompedon, until identified as the Old Temple of Athena Polias (Athena of the City). This is the most ancient building uncovered on the Acropolis; it was originally a simple sanctuary dating from the remotest times. The modest Doric temple of limestone was restored in the sixth century BC by Peisistratus, who embellished it by adding a colonnade and pediments depicting a Battle of the Giants, while its opisthodomos served as the Athenian Treasury.

In this heap of stones, enclosed by a railing, we can distinguish two bases in poros for the support of wooden pillars belonging to the Mycenaean megaron (palace) of the first King of   Athens . This was the center of the public life of the citadel and extended as far as the north wall of the Erechtheion. A flight of rock-cut steps built in Pelasgic times connected the megaron and the Acropolis with the lower city. Later, in historical times, on these Mycenaean vestiges was raised the above mentioned Temple of Athena Polias, a rectangle of 32.80 m. long, that is 100 feet, whence its name of “Hecatompedon” (temple of a hundred feet). This temple was rebuilt after it was destructed during the persian invasion but it appears that after the completion of the Erechtheion it became useless and an encumbrance, and was finally destroyed in 406 BC.

Opposite the ruins of the Old Temple of Athena Polias and close to the seventh column of the Parthenon, there is an inscription which reads: This spot was consecrated, after being indicated by an oracle, to the Fruitful Earth. Exactly on this spot was a statue of Earth beseeching Zeus to send rain. Nearby is a circular base, which formerly bore the statues of Conon and his son Timotheus and farther along is the base of a statue dedicated to Hermolycos, son of Deitrephes.

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The Acropolis – Athens, Goddess Athena

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Archaeologists tell us that the original city of Athens was situated on the Acropolis. Even in classical times, the Athenians still referred to this area as “the City.” The city of Athens and its patron goddess emerge into the light of history as inseparably coupled. In Mycenaean times each city was built around a central palace, and each palace was under the protection of its patron goddess. Athena was the goddess of the palace on the Acropolis. The names of the city and its goddess are essentially the same: Athena was Athens, and Athens was Athena. She was “The Athenian.” The ancient Athenians seem to have exhibited, during much of their history, precisely those virtues which they traditionally attributed to her. This may be because, when the Athenians imagined their goddess, they did so in their own image.

According to the myth, Zeus fell in love with a beautiful titaness, Metis (“Cunning Intelligence”). Although she repeatedly changed her shape to avoid his unwelcome attentions, as was his way, he persisted. In the end he caught up with her and raped her.

An oracle then announced that Metis would bear Zeus two children: first a daughter then, a son, and the son would be mightier than his father. Just as Zeus had once overthrown and dispossessed his own father, Chronos, so he was destined in his turn, to be overthrown by his own son. In a desperate attempt to avoid sharing his father’s fate, Zeus gave Metis a potion of drugged ambrosia, and then swallowed her whole.

Some time afterwards a terrible headache came upon him. In great pain, he sought the advice of Hermes, whose only suggestion was that Hephaestos, the smith of the gods, should open his head in order to allow the cause of his pain to escape. Zeus was so desperate that even this drastic remedy was preferable to doing nothing, and Hephaestos was duly summoned to cleave open Zeus’ head with his mighty axe. When he did so, to the astonishment of all the immortals, Athena sprang out with a great war-cry, fully-formed, wearing armour and bearing arms.

Zeus’ daughter not only became the patron of many arts at that time normally considered masculine preserves, such as ceramics, she was also credited with a distinctly unfeminine warlike nature. When the Olympian gods were faced with a titanic struggle against the giants, Athena played a major role in the war, defeating the giant Enkelados in single combat. She came to be depicted not merely as a virgin goddess, but, as an ancient Roman writer put it, as a virago: as a female capable of playing a leading role in a world dominated by men.

It came to be said that the reason for the birth of this goddess lay in a wager between Zeus and his consort, Hera, as to which of them could generate the better progeny entirely alone and unaided. By herself, Hera managed to produce only the crippled god, Hephaestos and a monster; while Zeus was able to bring forth, in Athena, one of the greatest of the Immortals.

This seems to have been a picturesque reference to a widespread belief, which was to appear later in the works of the philosopher Aristotle: that the father alone is responsible for generating his children, and for providing them with their inherited characteristics, and that their mother affords them nothing more than a temporary shelter and sustenance in her womb during her pregnancy.

This is a striking example of the strong climate of male chauvinism which dominated the early classical period in ancient Greece, which is very evident in myth and legend.

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Why Many Choose 25 ACP Ammunition Over Other Choices

For those who own an early blowback pistol, a gun that fails to include a breech locking mechanism, you should consider purchasing bulk 25 ACP ammo. The straight-walled, semi-rimmed cartridge was first offered to the public back in 1905. A creation of John Browning, the particular gun cartridge has a recessed extractor groove style and design to guarantee the extractor grabs this ammo cartridge correctly. The smallest centerfire handgun round presently being made, this type of cartridge is intended for semi-automatic handguns and is a good choice for people enthusiastic about purchasing a pistol for self defense reasons, since consistency is a problem with some rimfire gun cartridges.

You can quite easily carry a pistol using this kind of ammunition inside a handbag and / or jean pocket and also users really like that they may select from different loads, making it possible for an individual to choose the proper round penetration and also expansion for their particular demands. Individuals must always buy 25 ACP ammo and then spend time evaluating the various types to determine which they will be comfortable with. Many companies supply the ammunition in varying round amounts. If an individual purchases in big amounts, the purchase price per round decreases considerably. If an individual purchases twenty-five rounds, they might discover they are having to pay twice the purchase price for every round than when they buy one thousand rounds at the same time. Take this into account as you go to purchase as you never want to spend more than you really need to.

Get The Aid Of A Advertising And Marketing Company

When you have 3 bedroom apartments for sale, you might want to start using a property marketing company to ensure that your residences are going to be sold speedily. These companies possess all the resources required to advertise your residences and ensure you dig up the appropriate buyers.

Nowadays, it can be challenging for any buyer to locate the correct house and then for the seller to obtain the suitable buyer. Presently there are so many different houses sold at any time, therefore it may be nearly impossible for someone to locate the ideal place. As opposed to basically placing an advertisement for the condominiums on the internet and waiting for anyone to notice it, if you use a marketing company you can find they’ll guide you in finding buyers for every single one of your apartments quickly. They’ll be ready to sift through the potential buyers to make sure they’ll have the ability to pay for the residence and that they’re going to end up being the people you desire moving into your own residences. For instance, in case you own a significant, set of condominiums, you’re most likely going to prefer customers that do not have any kind of a criminal history. A marketing business will help you on this.

In case you are selling your own residences, never strive to complete it on your own. Let a marketing business aid you so that you can choose the best purchasers swiftly.

A Change of Pace in Athens Greece

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When someone mentions a holiday in Greece, the first thing that pops up in most people’s minds is sandy beaches and sparkling clean water. With a coastline 13,676 kilometers long, there is certainly a beach to suit every taste. However, Greece is also known for its capital  city ,  Athens ; a buzzing metropolis that never sleeps. Apart from the many fine hotels that are available, there is also alternative accommodation such as studios or apartments for a more affordable stay. For the tourist who wants to experience this city up close and work up a sweat at the same time, the best way is to rent a bike.

There are many cycling enthusiasts willing to take the challenge in a foreign country. Greece has many cyclists of its own and a plethora of agencies renting bikes or offering bike tours. All you have to do is decide how you want to do it; on your own or with a group. Since  Athens , like any big metropolis, has constant traffic congestion, cycling will certainly give you the freedom you’re looking for. Once you have studied your maps, you will be ready to zip in and out of traffic and discover secrets of the city that are off the beaten track.

Right in the heart of this modern city lie the ruins of an ancient civilization. As you head towards the city centre, you cannot miss the majestic hill of the Acropolis, a world heritage site. Sitting proudly at the top of the hill, is the famous columned structure of the Parthenon, which was built in honor of the goddess Athena. The hill and surrounding area abounds with the splendid remains of the past such as the ancient theatre of Herodes Atticus, the Erectheion and the Agora, the marketplace of ancient  Athens . All roads and narrow alleys lead you to these proud remains and reveal the mysteries of a distant world that is set amidst a modern city.

Along the way, you will find people and places to accommodate you on your tour. There are many roads that are off limits to cars as well as wide pedestrian pathways that are bicycle-friendly. Of course, during high season, the streets are dotted with people from all walks of life who come here to see the sights and experience the culture. The cafes and many eateries overflow with tourists while the locals, most of them fluent in English, are friendly and welcoming. Various artists and musicians are also there to entertain the crowds and shops spilling over with beautiful souvenirs.

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Philadelphia- the New Athens

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A city not only known as the city of American freedom or the birthplace of America but also known for the revolutionary role it has played since centuries. Welcome to Philadelphia, a life-size city in Pennsylvania and the birthplace of America. Philadelphia is often referred as the New Athens, the name first suggested for the work done by the famous native of the city Benjamin Franklin. Rightly so as Benjamin Franklin was responsible for the country’s first insurance company, the city’s first public library and the first fire department; Franklin also played a great role in establishing the city’s Postal system as well as inventing new conveniences such as bifocal lenses and the Franklin stove.

Philadelphia or “Philly” best known for its role in the American Revolutionary War saw the convening of the Continental Congress as well as the writing of the Declaration of Independence and the Constitution of the United States of America. Shortly after the nation’s inception took place in Philadelphia, it was named the nation’s capital between 1790 and 1800 before it was relocated to its present Washington D.C. Philly is now a big metropolitan which accommodates around 6.2 million inhabitants from almost all nationalities.

One of the unique factors about Philadelphia is that it is the most walkable city in the US and this factor is well used for the better part of it. Signs like “Walk! Philadelphia” well compliments the cities uniqueness and at the same time guide visitors toward shopping, dining, gallery perusing, cultural enjoyment, local must-sees and public transportation should it need to be taken. The city has two very walkable shopping districts as well as the walkable Benjamin Franklin Parkway, which is home to many museums, including the Franklin Institute and the Philadelphia Museum of Art that was made famous in the Rocky series of movies.

Its geographic location makes Philadelphia accessible by all modes of transport. The Philadelphia International airport is a busy one and you can find regular flights to almost all the locations. You can even enjoy the road trip to Philadelphia. Moreover as a visitor you can find hotels for every budget and if by any chance you are on a tight budget you can definitely find a suitable place in the Philadelphia districts. There is a place for every budget in Philadelphia. Some of the regular facilities offered by the hotels in Philadelphia include air conditioned rooms, car rentals, airport pick and drop facilities, swimming pools, health clubs, spas, restaurants etc. The city provides a unique nightlife to all and that definitely means that you can take a ballet in the nation’s oldest grand opera house as well as knock back a Pabst and a shot of swill for three bucks. In all Philadelphia makes a great city for all and if you haven’t taken a note of that you better mark it in your next holiday destination.

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Athens Syntagma Square – Athens City Center

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The heart of present day Athens is fashionable Plateia Syntagmatos which lies below the imposing mass of the Old Royal Palace. Plateia Syntagmatos, which translated means Constitution Square, commemorates the constitution granted by Othon I in a proclamation from the balcony of the Palace on the night of 3rd September 1843.

The OLD ROYAL PALACE, which since 1935 has housed the Parliament, was designed as the residence of King Othon, at his own and his father’s expense, by the Bavarian architect Friedrich Garther and built between 1834 and 1842.

At the foot of the west facade of the Old Palace is a large square bounded on three sides by walls on which, in evocation of the ancient custom of hanging the victor’s shield in the temple, are set bronze shields flanked by the names of the many victories won by Hellenic arms since National Independence. Built into the center of the retaining wall is the TOMB OF THE UNKNOWN SOLDIER, a relief impressive in its simplicity, which depicts a dying hoplite. This work is by the sculptors Constantinos Demetriades (1881-1943) and Phokion Rok (1886-1942), and was unveiled on 25th March (National Independence Day) 1932.

South of Plateia Syntagmatos lies Leophoros Amalias, which is so called after King Othon’s consort, who, with the horticulturist Friedrich Schmiedt, created the delectable retreat adjoining the Old Royal Palace that we know today as the NATIONAL GARDEN. The National Garden is open daily from sunrise to sunset and the shade of its multitudinous trees provides a cool and peaceful oasis in the heart of the city.

On the east side of the Garden are the busts of Capodistrias and Jean-Gabriel Eynard, a great Swiss philhellene who donated large sums of money to the cause of Greek Independence. Both these busts are the work of the famous Pelopennesian loannis Kossos. Other busts in the National Garden are those of three leading Greek poets of the 19th century: Dionysius Solomos of Zante, who is considered the national poet; Aristotle Valaoritis, also a native of the Ionian Islands, and Jean Moreas, which was the nom-de-plume of loannis Papadiamantopoulos, an Athenian who lived the greater part of his life in Paris.

Contiguous to the National Garden is a large public park called ZAPPEION after the brothers Evangelos and Constantinos Zappas of Epirus, who donated it with its splendid exhibition hall to the Nation. On either side of the entrance to the exhibition hall stand statues of the donors, that of Evangelos by loannis Kossos; that of Constantinos by Georgios Vroutos. Among the many pieces of statuary by famous sculptors is the bust of loannis Varvakis by the master Leonidas Drossis. Varvakis is best known as the founder of the renowned boys’ school, the Lykeion Varvakeion, for the endowment of which he bequeathed his huge fortune. Other busts include those of Constantinos Paparrighopoulos, the greatest historian of Modern Greece, of Stephan Dragoumis, the most prominent political personality during the Macedonian struggle (1903-1909), and of George Souris, the leading satirical poet of his times.

A short distance from Plateia Syntagmatos, on the right of Odhos Panepistimiou, we come to a Renaissance edifice of Italian inspiration. This is the NUMISMATIC MUSEUM, which contains a rich collection of Greek, Roman and Byzantine coins, cameos and seal-stones. Built by the noted architect Erst Ziller in 1878, it was the private residence of the illustrious archaeologist Henry Schliemann.

Still keeping on the right-hand side we come to a five-storeyed building situated at the corner of this street and Odhos Omirou. Here are the premises of the ARCHAEOLOGICAL SOCIETY, built entirely in marble. The classical motif of the magnificent bronze door with its richly painted and gilded surround and the ceiling coffered in a delicate blue and gold deserve the greatest admiration. Besides creating the first National Archaeological Museum the Society, which was founded in 1837, has excavated sites all over the country.

Immediately after the Archaeological Society’s premises stands the ROMAN CATHOLIC CATHEDRAL. As the Latin inscription shows, the cathedral was begun in 1853, completed in 1887, and dedicated to St. Dionysius Areopagite. It is a three-naved basilica designed by Leo von Klenze (1784-1864), Bavarian Court architect and master-plan ner of modern Athens, and built under the direction of Lysander Kaftanzoglou (1811-1885), the outstanding Greek architect of the period.

Adjoining this edifice is the OPHTHALMIC HOSPITAL, a Byzantine-style construction designed by Theophil Hansen (1813-1891, the younger of two Danish brothers, both distinguished architects), in 1847, and completed by Lysander Kaftanzoglou four years later.

Just beyond the Ophthalmic Hospital is an ensemble of neo-Classical buildings: on the right the Academy, in the middle the University, and on the left the National Library. All three were gifts to the Nation from wealthy patriots; they are the most sumptuous monuments of Modern Greece.

The HELLENIC ACADEMY OF ARTS AND SCIENCES, a meticulously accurate reproduction of an edifice of the Classical period erected in the graceful Ionic order by Theophil Hansen at the expense of Baron Georgios Sinas, was begun in 1859 and completed in 1875.

The nine sculptured pediments and all the statues before the Academy are the work of the Athenian master Leonidas Drossis. The relief in the central pediment, which portrays The Birth of Athena, and the two gigantic statues of Apollo (right) and Athena (left) standing on tall columns, one on either side of the principal facade, are particularly impressive. The seated figures flanking the short flight of steps leading to the portico represent the philosophers Socrates (right) and Plato (left).

The portico consists of a double row of columns. The coffered ceiling is painted in bright blue and gold and the door opening into the vestibule has a surround of classical inspiration executed in brilliant color and gilding. A statue of the donor Baron Sinas stands on the right of the vestibule, while the interior of the Academy Hall is decorated with eight superb panels by the Oldenburg painter Christian Griepenkerl (1839-1916), depicting scenes from the Myth of Prometheus.

Visitors to the University will be surprised to see a statue of William Ewart Gladstone, standing on the right of the lawn surrounding the forecourt. The dedication on the plinth of this statue immortalizes the prominent part played by the great British statesman in the deliverance of Epirus and Thessaly from Turkish oppression, and their return to the Motherland in 1881.

The statues at the top of the steps leading to the entrance commemorate the great philologist Korais (1748-1833), ardent patriot and “father” of the Modern Greek literary language (right), and Capodistrias (1776-1831), first Head of State (1827-1831) and one of the major architects of modern Greece.

The UNIVERSITY OF ATHENS was founded in 1836, and was initially established in a large house which Schaubert and Cleanthes had built in Plaka (the old quarter of Athens) when they first came to Athens in 1831. This building, at the corner of Odhos Prytaneiou and Odhos Tholou, is still standing and is converted into a museum devoted to the earlier history of the University. The present University buildings were designed by Christian Hansen and the foundation stone laid by King Othon in 1839. The central building was ready for use in 1842, but owing to lack of funds, the buildings as a whole were not completed until 1850.

A colonnade with a handsome portico in Pentelic marble fronted by two Ionic columns with gilded capitals, and a coffered ceiling in blue and gold in harmony with the classical motif of a painted and gilded door surround, gives access to the interior of the main building.

On the upper part of the wall a fresco by the celebrated Austrian painter Karl Rahl (1812-1865) shows the resurgence of arts and sciences under King Othon. Statues of two national heroes, Patriarch Grigorios and the martyred poet Rhigas Pheraios, stand respectively at the right and left angles of the facade.

The NATIONAL LIBRARY, which is built of Pentelic marble on a foundation of poros, consists of a central building in the form of a Doric temple, with two wings. It was planned by Theophil Hansen in 1887 and the work executed under the supervision of Ernst Ziller, at the expense of the Valianos brothers of Cephalonia in 1901. A statue of one of these munificent benefactors, Panayis, stands outside the central building, and those of his two brothers Andreas and Maris inside the entrance hall. All three statues are the work of Georgios Bonanos.

The eminent philologist Andreas Moustoxidis on the island of Aegina formed the nucleus of the Library in 1827. The books were brought to Athens in 1833 and stored in the beautiful church of St. Eleutherius (the “Little Cathedral”). In 1842 they were removed to the first floor of the central building of the University – which had just been completed – where they remained until the National Library was inaugurated in 1903.

In recent years many fine nineteenth century buildings have been demolished and unimaginative concrete structures built on the sites, so that with the exception of the Ionian Bank of Greece on one corner of Odhos Pezmazoglou and the former buildings of the Arsakeion College for Girls (founded in 1836) on the other corner over the Doric portico, built at the expense of Apostolos Arsakis of Epirus in 1848, nothing remains of the splendid buildings that once lined both sides of this street of central Athens.

Continuing along Odhos Panepistimiou for a short distance, we turn right into Odhos Patission. A few hundred meters further down, on our right, stands a construction in the finest Pentelic marble, in which two educational institutions of University status are established: The POLYTECHNIC SCHOOL (Civil, Mechanical, Electrical, Naval, Chemical and Mining Engineering, Architecture, and Topography) and the SUPERIOR SCHOOL OF FINE ARTS (Drawing, Painting, Sculpture, Engraving, etc.). Two wings in the Doric order serve as propylaea to the central building of two storeys, the lower erected in the Doric order, the upper in Ionic. This edifice is the work of Lysander Kaftanzoglou, who built it between 1862 and 1880, and owes its name -METSOVION POLYTECHNEION- to the fact that the principal donors Nicholaos Stournaras, Michalis Tositsas and his widow Helen, were natives of Metsovo in Epirus.